The use of implantable biomedical devices such as pacemakers and artificial joints has increased dramatically in recent years, improving quality of life of countless patients. However, despite the advantages provided by biomedical implants, the formation of fibrotic tissue at the site of these implants poses significant challenges, particularly for neuroprosthetic devices such as cochlear implants (CIs).  To address this issue, we investigate the use of poly(zwitterionic) coatings to reduce the foreign body response (FBR) to implanted biomedical devices. Zwitterionic polymers, which contain both positively and negatively charged groups, are hydrophillic materials that exhibit anti-adhesive/anti-fouling properties with respect to a range of biomolecules. In this project, we seek to create coatings for CIs that will prevent FBR and reduce fibrosis near the implant. Additionally, we anticipate that the results of this study may be extended to additional biomedical implants as well.